Whole genome amplification (WGA) is a technology for non‐selective amplification of the
whole genome sequence, first appearing in 1992. Its primary purpose is to amplify and …

Objectives To identify the role of next-generation sequencing (NGS) in male infertility, as
advances in NGS technologies have contributed to the identification of novel genes …

The pace of the sequencing and computational assembly of novel reference genomes is
accelerating. Though DNA sequencing technologies and assembly software tools continue …

The interpretation of DNA mixtures remains a significant challenge in the analysis of forensic
evidence. The ability to selectively identify, collect, and analyze single cells or groups of …

Microorganisms are highly regarded as a prominent source of natural products that have
significant importance in many fields such as medicine, farming, environmental safety, and …

A high incidence of aneuploidy is observed in vitro fertilization (IVF)-derived embryos, but
the formation and repair mechanisms are unknown. Here, we investigated the effects of …

In men with oligozoospermia, Robertsonian translocations (RobTs) are the most common
type of autosomal aberrations. The most commonly occurring types are rob (13; 14) and rob …

Purpose The purpose of this study was to develop a feasible approach for single sperm
isolation and chromosome analysis by next-generation sequencing (NGS). Methods Single …

To draw robust conclusions when trace DNA samples are detected in complex cases, it is
essential to successfully recover and genotype short tandem repeats (STRs) from trace …

In this cross-sectional prospective study, advanced next-generation sequencing technology
was used to compare the molecular karyotyping of individual human sperm cells in infertile …