Objectives To evaluate associations between different definitions of prediabetes and the risk
of cardiovascular disease and all cause mortality. Design Meta-analysis of prospective …

Diabetes mellitus is one of the most important public health challenges of the twenty-first
century. Until the past decade, it has been seriously underrated as a global health threat …

Importance Individuals with prediabetes are at increased risk of developing type 2 diabetes,
chronic kidney disease, and cardiovascular disease. The incidence and prevalence of type …

Background The projected rise in the incidence of type 2 diabetes mellitus (T2DM) could
develop into a substantial health problem worldwide. Whether diet, physical activity or both …

Objectives To assess diagnostic accuracy of screening tests for pre-diabetes and efficacy of
interventions (lifestyle or metformin) in preventing onset of type 2 diabetes in people with pre …

OBJECTIVE To summarize the evidence on effectiveness of translational diabetes
prevention programs, based on promoting lifestyle change to prevent type 2 diabetes in real …

Background Intermediate hyperglycaemia (IH) is characterised by one or more
measurements of elevated blood glucose concentrations, such as impaired fasting glucose …

Type 2 diabetes mellitus (T2DM) is associated with a two-to four-fold increased risk of
developing cardiovascular disease (CVD) and microvascular complications, which may …

For over 100 years, the oral glucose tolerance test (OGTT) has been the cornerstone for
detecting prediabetes and type 2 diabetes (T2DM). In recent decades, controversies have …

Background There is controversy over the usefulness of prediabetes as a diagnostic label.
Using data from US National Health and Nutrition Examination Surveys (NHANES) between …