Modern tools for rapid diagnostics of antimicrobial resistance

A Vasala, VP Hytönen, OH Laitinen - Frontiers in cellular and infection …, 2020 - frontiersin.org
Fast, robust, and affordable antimicrobial susceptibility testing (AST) is required, as roughly
50% of antibiotic treatments are started with wrong antibiotics and without a proper …

Sequencing-based methods and resources to study antimicrobial resistance

M Boolchandani, AW D'Souza, G Dantas - Nature Reviews Genetics, 2019 - nature.com
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging

Ö Baltekin, A Boucharin, E Tano… - Proceedings of the …, 2017 - National Acad Sciences
The emergence and spread of antibiotic-resistant bacteria are aggravated by incorrect
prescription and use of antibiotics. A core problem is that there is no sufficiently fast …

Single-cell microfluidic impedance cytometry: From raw signals to cell phenotypes using data analytics

C Honrado, P Bisegna, NS Swami, F Caselli - Lab on a Chip, 2021 - pubs.rsc.org
The biophysical analysis of single-cells by microfluidic impedance cytometry is emerging as
a label-free and high-throughput means to stratify the heterogeneity of cellular systems …

A fast impedance-based antimicrobial susceptibility test

DC Spencer, TF Paton, KT Mulroney, TJJ Inglis… - Nature …, 2020 - nature.com
There is an urgent need to develop simple and fast antimicrobial susceptibility tests (ASTs)
that allow informed prescribing of antibiotics. Here, we describe a label-free AST that can …

New and developing diagnostic technologies for urinary tract infections

M Davenport, KE Mach, LMD Shortliffe… - Nature Reviews …, 2017 - nature.com
Timely and accurate identification and determination of the antimicrobial susceptibility of
uropathogens is central to the management of UTIs. Urine dipsticks are fast and amenable …

Rapid pathogen-specific phenotypic antibiotic susceptibility testing using digital LAMP quantification in clinical samples

NG Schoepp, TS Schlappi, MS Curtis… - Science translational …, 2017 - science.org
Rapid antimicrobial susceptibility testing (AST) is urgently needed for informing treatment
decisions and preventing the spread of antimicrobial resistance resulting from the misuse …

Early detection and classification of live bacteria using time-lapse coherent imaging and deep learning

H Wang, H Ceylan Koydemir, Y Qiu, B Bai… - Light: Science & …, 2020 - nature.com
Early identification of pathogenic bacteria in food, water, and bodily fluids is very important
and yet challenging, owing to sample complexities and large sample volumes that need to …

[HTML][HTML] Current and emerging techniques for antibiotic susceptibility tests

K Syal, M Mo, H Yu, R Iriya, W Jing, S Guodong… - Theranostics, 2017 - ncbi.nlm.nih.gov
Infectious diseases caused by bacterial pathogens are a worldwide burden. Serious
bacterial infection-related complications, such as sepsis, affect over a million people every …

Rapid methods for antimicrobial resistance diagnostics

GD Kaprou, I Bergšpica, EA Alexa, A Alvarez-Ordóñez… - Antibiotics, 2021 - mdpi.com
Antimicrobial resistance (AMR) is one of the most challenging threats in public health; thus,
there is a growing demand for methods and technologies that enable rapid antimicrobial …