The development of new strategies and chemical reactions continues to be a major focus of
research efforts in the modern synthetic organic community. 1 Of the various types of …

The oxazolidinones are a new and potent class of antimicrobial agents with activity mainly
against Gram-positive strains. The commercial success of linezolid, the only FDA-approved …

Trisubstituted thiazoles were synthesized and studied for their antimicrobial activity and
supported by theoretical calculations. In addition, MIC, MBC and MFC were also tested …

A series of new coumarin based thiazoles were synthesized by the microwave irradiation of
thiocarbohydrazide, aldehydes and 3-(2-bromoacetyl) coumarins. Structures of all the …

Benzothiazole analogues are of interest due to their potential activity against malarial and
microbial infections. In search of suitable antimicrobial and antimalarial agents, we report …

A series of nineteen thiazole Schiff base derivatives 2a-2s were synthesized (Scheme 1)
and elucidated by spectral analyses (IR, 1 H NMR and HRMS). The evaluation of their …

The main advances in the chemistry of acetylene in superbasic media achieved over the last
five years are analyzed. Particular emphasis is placed on the ethynylation of aldehydes and …

Multicomponent reactions (MCRs) have emerged as an efficient and eco-safe approach in
organic synthesis. The influential nature of this approach has been well established in the …

An efficient method for the regioselective synthesis of pharmacologically relevant
polysubstituted Δ2‐isoxazolines is based on the copper‐mediated direct transformation of …

In this letter, an unprecedented cross-coupling reaction between copper carbene and
nitroso radical has been developed. This radical-carbene coupling reaction (RCC reaction) …