Bioanalysis based on optical imaging has gained significant progress in the last few
decades. Luminescence probes are capable of detecting, monitoring, and tracing particular …

Breast cancer progression is a complex process involving the primary tumor and its
microenvironment supported by a vascular network. Multicellular spheroids closely mimic in …

Over the past century, the chick embryo model, historically employed for research in
developmental biology, has become a valuable tool for cancer research. The characteristics …

Simple Summary Animal testing is an important method in medical research and the
development of new drugs (pharmaceuticals). Classic animal models feature mice or rats …

Background: Preclinical cell tracking is enhanced with a multimodal imaging approach.
Bioluminescence imaging (BLI) is a highly sensitive optical modality that relies on …

Metastatic lesions produced through the process of systemic tumor cell dissemination and
growth at distant sites are challenging to treat and the primary cause of patient mortality …

The high incidence of vascular and lymphatic metastasis is closely associated with poor
prognosis and mortality in cancer. Finding effective inhibitors to prevent pathological …

Tissue engineering and regeneration tackled by methods to determine the state, movement,
and fate of cells in vitro and in vivo revolutionized applied medicine. Thus, methods enabling …