Background Schizophrenia is a complex psychiatric disorder that includes positive and
negative symptoms but also debilitating cognitive deficits. Current pharmacological …

Peripheral inflammation, defined as inflammation that occurs outside the central nervous
system, is an age-related phenomenon that has been identified as a risk factor for …

While some individuals age without pathological memory impairments, others develop age‐
associated cognitive diseases. Since changes in cognitive function develop slowly over time …

Aging is characterized by a progressive loss of brain volume at an estimated rate of 5% per
decade after age 40. While these morphometric changes, especially those affecting gray …

Chronic inflammation of the central nervous system (CNS), termed neuroinflammation, is a
hallmark of aging and a proposed mediator of cognitive decline associated with aging …

Background With the challenges that aging populations pose to health care, interventions
that facilitate alleviation of age-related morbidities are imperative. A prominent risk factor for …

Cromolyn is a known mast cell stabilizer and is approved for treatment of asthma and for
other allergic indications. Cromolyn, in a new redesigned dry powder formulation, is being …

The mammalian nervous system is impacted by aging. Aging alters brain architecture, is
associated with molecular damage, and can manifest with cognitive and motor deficits that …

Background The neuroimmune system is required for normal neural processes, including
modulation of cognition, emotion, and adaptive behaviors. Aberrant neuroimmune activation …

To establish causal evidence for the association of adiposity-related metabolic abnormalities
with brain volumes, and the risks of dementia and stroke, we applied 1-and 2-sample …