Survival in patients with pulmonary arterial hypertension (PAH) is closely related to right
ventricular (RV) function. Although pulmonary load is an important determinant of RV …

Ventricular failure manifests in many forms, its underlying physiology ranging from overt left
ventricular (LV) systolic dysfunction to isolated right ventricular (RV) diastolic dysfunction …

Background—In vitro studies suggest that phosphorylation of titin reduces myocyte/myofiber
stiffness. Titin can be phosphorylated by cGMP-activated protein kinase. Intracellular cGMP …

Objective: Pulmonary hypertension may be encountered in the intensive care unit in patients
with critical illnesses such as acute respiratory distress syndrome, left ventricular …

In the veterinary literature, pulmonary hypertension (PH) has been echocardiographically
defined as pulmonary arterial systolic pressure greater than approximately 30 mm Hg. 1–6 …

The nitric oxide (NO) signalling pathway is altered in cardiovascular diseases, including
systemic and pulmonary hypertension, stroke, and atherosclerosis. The vasodilatory …

Pulmonary arterial hypertension (PAH) is a vascular disorder associated with high morbidity
and mortality rate and is characterized by pulmonary vascular remodeling and increased …

Abstract Background/Aims: Pulmonary hypertension (PHT) has been reported to be high
among end-stage renal disease (ESRD) patients. This study evaluated PHT in ESRD …

Natriuretic peptides play a fundamental role in cardiovascular homeostasis by modulation of
fluid and electrolyte balance and vascular tone. C-type natriuretic peptide (CNP) represents …

Besides pumping, the heart participates in hydro-sodium homeostasis and systemic blood
pressure regulation through its endocrine function mainly represented by the large family of …