Carbohydrate-based macromolecular biomaterials

L Su, Y Feng, K Wei, X Xu, R Liu, G Chen - Chemical Reviews, 2021 - ACS Publications
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

Nano based drug delivery systems: recent developments and future prospects

JK Patra, G Das, LF Fraceto, EVR Campos… - Journal of …, 2018 - Springer
Nanomedicine and nano delivery systems are a relatively new but rapidly developing
science where materials in the nanoscale range are employed to serve as means of …

Stimuli-responsive gene delivery nanocarriers for cancer therapy

Q Zhang, G Kuang, W Li, J Wang, H Ren, Y Zhao - Nano-Micro Letters, 2023 - Springer
Gene therapy provides a promising approach in treating cancers with high efficacy and
selectivity and few adverse effects. Currently, the development of functional vectors with …

Polysaccharide nanoparticles: From fabrication to applications

A Plucinski, Z Lyu, BVKJ Schmidt - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Polysaccharides have attracted considerable attention in a broad range of applications in
recent years, which is due to their remarkable features such as biocompatibility …

Tumor microenvironment targeted nanotherapeutics for cancer therapy and diagnosis: A review

S Thakkar, D Sharma, K Kalia, RK Tekade - Acta biomaterialia, 2020 - Elsevier
Recent findings suggest that the cellular and extracellular materials surrounding the
cancerous cells from an atypical tumor microenvironment (TM) play a pivotal role in the …

Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

The intracellular and extracellular microenvironment of tumor site: the trigger of stimuli‐responsive drug delivery systems

X Jing, H Hu, Y Sun, B Yu, H Cong, Y Shen - Small Methods, 2022 - Wiley Online Library
The tumor microenvironment (TME), including intracellular and extracellular
microenvironment, contains many biochemical indicators (such as acidity/alkalinity, oxygen …

Hyaluronic acid for anticancer drug and nucleic acid delivery

F Dosio, S Arpicco, B Stella, E Fattal - Advanced drug delivery reviews, 2016 - Elsevier
Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible,
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …

PEG—A versatile conjugating ligand for drugs and drug delivery systems

A Kolate, D Baradia, S Patil, I Vhora, G Kore… - Journal of controlled …, 2014 - Elsevier
Polyethylene glycol (PEG) conjugation is a rapidly evolving strategy to solve hurdles in
therapeutic delivery and is being used as an add-on tool to the traditional drug delivery …

Polysaccharide-based nanoparticles for theranostic nanomedicine

M Swierczewska, HS Han, K Kim, JH Park… - Advanced drug delivery …, 2016 - Elsevier
Polysaccharides are natural biological molecules that have numerous advantages for
theranostics, the integrated approach of therapeutics and diagnostics. Their derivable …