Phospholipases As (EC 3.1. 1.4) are wide spread in Nature and are found both within and
without the cell (see for reviews Shen and Law 1979; van den Bosch 1980). In this review …

Snakebite envenomation is a neglected global health problem, causing substantial mortality,
disability, and psychological morbidity, especially in rural tropical and subtropical zones …

Specificity of Proteolysis presents a survey and conclusions on the action or proteinases-
enzymes which are cleaving proteins or peptides. The specificity of proteinases which is …

Center for Biochemical and Biophysical Sciences and Medicine and Departments of
Biological Chemistry, Pathology, and Radiology, Harvard Medical School, and Brigham …

The complete amino acid sequence of Crotalus adamanteus venom phospholipase A2-
alpha has been determined by analysis of the five tryptic peptides from the citraconylated …

Taipoxin (taipan toxin), purified from the venom of the Australian taipan (Oxyuranus s.
scutellatus) by gel filtration on Sephadex G‐75 followed by column zone electrophoresis, is …

The phospholipase A2 (PLA2) inhibitor Varespladib (LY315920) and its orally bioavailable
prodrug, methyl-Varespladib (LY333013) inhibit PLA2 activity of a wide variety of snake …

Necrosis of skeletal muscle is produced by two types of snake venom components: single
chain peptides consisting of 42–44 amino acid residues and phospholipases A 2 …

Many cell types of therapeutic interest, including myoblasts, exhibit reduced engraftment if
cultured prior to transplantation. This study investigated whether polymeric scaffolds that …

Recent studies revealed that animal toxins with unrelated biological Functions often possess
a similar architecture. To tentatively understand the evolutionary mechanisms that may …