Harnessing the process of natural selection to obtain and understand new microbial
phenotypes has become increasingly possible due to advances in culturing techniques …

Fluxomics is an innovative-omics research field that measures the rates of all intracellular
fluxes in the central metabolism of biological systems. Fluxomics gathers data from multiple …

Adaptive laboratory evolution (ALE) is an evolutionary engineering approach in artificial
conditions that improves organisms through the imitation of natural evolution. Due to the …

Environmental sustainability is an increasingly important issue in industry. As an
environmentally friendly and sustainable way, constructing microbial cell factories to …

Bioprocessing offers a sustainable and green approach to the production of chemicals.
However, a bottleneck in introducing bioprocesses is cell factory development, which is …

Green routes are indispensable for a sustainable production of energy, chemicals and
materials, and health and nutrition products from renewable resources. Naturally, microbes …

Microorganisms are effective platforms for the production of a variety of chemicals including
biofuels, commodity chemicals, polymers and other natural products. However, deep cellular …

Motivation Synthetic microbial communities begin to be considered as promising
multicellular biocatalysts having a large potential to replace engineered single strains in …

Biological production of chemicals is an attractive alternative to petrochemical-based
production, due to advantages in environmental impact and the spectrum of feasible targets …

Microbial cell factories have proven to be an economical means of production for many bulk,
specialty, and fine chemical products. However, we still lack both a holistic understanding of …