Spontaneous dog osteoarthritis—a One Medicine vision

RL Meeson, RJ Todhunter, G Blunn, G Nuki… - Nature Reviews …, 2019 - nature.com
Osteoarthritis (OA) is a global disease that, despite extensive research, has limited treatment
options. Pet dogs share both an environment and lifestyle attributes with their owners, and a …

A 2022 systematic review and meta-analysis of enriched therapeutic diets and nutraceuticals in canine and feline osteoarthritis

M Barbeau-Gregoire, C Otis, A Cournoyer… - International journal of …, 2022 - mdpi.com
With osteoarthritis being the most common degenerative disease in pet animals, a very
broad panel of natural health products is available on the market for its management. The …

Translational pain assessment: could natural animal models be the missing link?

MP Klinck, JS Mogil, M Moreau, BDX Lascelles… - Pain, 2017 - journals.lww.com
Failure of analgesic drugs in clinical development is common. Along with the current
“reproducibility crisis” in pain research, this has led some to question the use of animal …

Pain assessment in animal models of osteoarthritis

MJ Piel, JS Kroin, AJ Van Wijnen, R Kc, HJ Im - Gene, 2014 - Elsevier
Assessment of pain in animal models of osteoarthritis is integral to interpretation of a model's
utility in representing the clinical condition, and enabling accurate translational medicine …

[HTML][HTML] Characterization of osteoarthritis in cats and meloxicam efficacy using objective chronic pain evaluation tools

M Guillot, M Moreau, M Heit, J Martel-Pelletier… - The Veterinary …, 2013 - Elsevier
This study aimed to characterize osteoarthritis (OA)-related chronic pain and disability in
experimental cats with naturally occurring OA. Peak vertical ground reaction force (PVF) …

A prospective, randomized, masked, and placebo-controlled efficacy study of intraarticular allogeneic adipose stem cells for the treatment of osteoarthritis in dogs

R Harman, K Carlson, J Gaynor, S Gustafson… - Frontiers in Veterinary …, 2016 - frontiersin.org
Osteoarthritis (OA) is a degenerative joint disease with a high prevalence in dogs.
Mesenchymal stem cells (MSCs) have been used to treat humans, dogs, and horses with …

[HTML][HTML] A prospective, randomized, double blind, placebo-controlled evaluation of the effects of eicosapentaenoic acid and docosahexaenoic acid on the clinical …

SJ Mehler, LR May, C King, WS Harris… - … Leukotrienes and Essential …, 2016 - Elsevier
Background Osteoarthritis (OA) in dogs is a prevalent and serious condition. The most
common treatment for the clinical signs of OA in dogs is the administration of nonsteroidal …

Forelimb and hindlimb ground reaction forces of walking cats: assessment and comparison with walking dogs

RJ Corbee, H Maas, A Doornenbal… - The Veterinary …, 2014 - Elsevier
The primary aim of this study was to assess the potential of force plate analysis for
describing the stride cycle of the cat. The secondary aim was to define differences in feline …

Dog owners' recognition of pain-related behavioral changes in their dogs

A Demirtas, D Atilgan, B Saral, S Isparta… - Journal of Veterinary …, 2023 - Elsevier
Pain management in veterinary medicine has been drawing considerable attention in recent
years. Although it is important to evaluate the daily behaviors of dogs while assessing …

Initial evaluation of nighttime restlessness in a naturally occurring canine model of osteoarthritis pain

D Knazovicky, A Tomas, A Motsinger-Reif… - PeerJ, 2015 - peerj.com
Chronic pain due to osteoarthritis (OA) can lead to significant disruption of sleep and
increased restlessness. Our objective was to assess whether naturally occurring canine OA …