[HTML][HTML] Genetics, pathophysiology, diagnosis, treatment, management, and prevention of migraine
Migraine is a neurological ailment that is characterized by severe throbbing unilateral
headache and associated with nausea, photophobia, phonophobia and vomiting. A full and …
headache and associated with nausea, photophobia, phonophobia and vomiting. A full and …
[HTML][HTML] Migraine treatment: current acute medications and their potential mechanisms of action
JJY Ong, M De Felice - Neurotherapeutics, 2018 - Elsevier
Migraine is a common and disabling primary headache disorder with a significant
socioeconomic burden. The management of migraine is multifaceted and is generally …
socioeconomic burden. The management of migraine is multifaceted and is generally …
Mechanism of action of paracetamol
Paracetamol (acetaminophen) is generally considered to be a weak inhibitor of the
synthesis of prostaglandins (PGs). However, the in vivo effects of paracetamol are similar to …
synthesis of prostaglandins (PGs). However, the in vivo effects of paracetamol are similar to …
Medication overuse and drug addiction: a narrative review from addiction perspective
TT Takahashi, R Ornello, G Quatrosi, A Torrente… - The journal of headache …, 2021 - Springer
Chronic headache is particularly prevalent in migraineurs and it can progress to a condition
known as medication overuse headache (MOH). MOH is a secondary headache caused by …
known as medication overuse headache (MOH). MOH is a secondary headache caused by …
Paracetamol versus placebo for knee and hip osteoarthritis
AO Leopoldino, GC Machado… - Cochrane Database …, 1996 - cochranelibrary.com
Background Paracetamol (acetaminophen) is vastly recommended as the first‐line
analgesic for osteoarthritis of the hip or knee. However, there has been controversy about …
analgesic for osteoarthritis of the hip or knee. However, there has been controversy about …
Selective COX-1 inhibition: A therapeutic target to be reconsidered
MG Perrone, A Scilimati, L Simone… - Current medicinal …, 2010 - ingentaconnect.com
Since cyclooxygenase (COX) isozymes discovery, many papers and reviews have been
published to describe the structural bases of COX inhibition, and to debate on the …
published to describe the structural bases of COX inhibition, and to debate on the …
Pharmacotherapy of low back pain: targeting nociceptive and neuropathic pain components
B Morlion - Current medical research and opinion, 2011 - Taylor & Francis
Aim: To review pharmacological management of chronic low back pain (LBP), with respect
to management of nociceptive and neuropathic components. Methods: Studies were …
to management of nociceptive and neuropathic components. Methods: Studies were …
Inhibition of human neutrophil oxidative burst by pyrazolone derivatives
The risk of agranulocytosis associated with the use of pyrazolone drugs at therapeutical
doses and for short periods of time has been considered to be very low. However, little or no …
doses and for short periods of time has been considered to be very low. However, little or no …
[PDF][PDF] Cyclooxygenase-3: axiom, dogma, anomaly, enigma or splice error? Not as easy as 1, 2, 3
A continued need to develop safe and effective analgesics and anti-inflammatory drugs fuels
the ongoing investigations of cyclooxygenase (COX). In addition, a long unanswered …
the ongoing investigations of cyclooxygenase (COX). In addition, a long unanswered …
Drug management of visceral pain: concepts from basic research
MP Davis - Pain research and treatment, 2012 - Wiley Online Library
Visceral pain is experienced by 40% of the population, and 28% of cancer patients suffer
from pain arising from intra‐abdominal metastasis or from treatment. Neuroanatomy of …
from pain arising from intra‐abdominal metastasis or from treatment. Neuroanatomy of …