Dual effect of immune cells within tumour microenvironment: pro-and anti-tumour effects and their triggers

AC Peña-Romero, E Orenes-Piñero - Cancers, 2022 - mdpi.com
Simple Summary The relationship between the immune system and tumours is currently one
of the most studied topics in the field of cancer. Previously, it was thought that a tumour could …

Mast cells in the tumor microenvironment

A Aponte-López, S Muñoz-Cruz - … Microenvironment: Hematopoietic Cells …, 2020 - Springer
Mast cells are tissue-resident, innate immune cells that play a key role in the inflammatory
response and tissue homeostasis. Mast cells accumulate in the tumor stroma of different …

Mast cell, the neglected member of the tumor microenvironment: role in breast cancer

A Aponte-López, EM Fuentes-Pananá… - Journal of …, 2018 - Wiley Online Library
Mast cells are unique tissue‐resident immune cells that secrete a diverse array of
biologically active compounds that can stimulate, modulate, or suppress the immune …

Triple-negative breast cancer with high levels of annexin A1 expression is associated with mast cell infiltration, inflammation, and angiogenesis

M Okano, M Oshi, AL Butash, E Katsuta… - International journal of …, 2019 - mdpi.com
Annexin A1 (ANXA1) is a phospholipid-linked protein involved in inflammation, immune
response, and mast cell reactivity. Recently, we reported that ANXA1 is associated with …

Mast cells as a target—A comprehensive review of recent therapeutic approaches

J Baran, A Sobiepanek, A Mazurkiewicz-Pisarek… - Cells, 2023 - mdpi.com
Mast cells (MCs) are the immune cells distributed throughout nearly all tissues, mainly in the
skin, near blood vessels and lymph vessels, nerves, lungs, and the intestines. Although MCs …

Poor response to neoadjuvant chemotherapy correlates with mast cell infiltration in inflammatory breast cancer

SM Reddy, A Reuben, S Barua, H Jiang, S Zhang… - Cancer immunology …, 2019 - AACR
Our understanding is limited concerning the tumor immune microenvironment of
inflammatory breast cancer (IBC), an aggressive form of primary cancer with low rates of …

Controversial role of mast cells in breast cancer tumor progression and angiogenesis

D Ribatti, T Annese, R Tamma - Clinical Breast Cancer, 2021 - Elsevier
Breast cancer is a neoplastic disease and is a cause of cancer-related mortality for women.
Among cellular and molecular regulators of the microenvironment, mast cells and vascular …

Mast cells in breast cancer angiogenesis

AM Cimpean, R Tamma, S Ruggieri, B Nico… - Critical reviews in …, 2017 - Elsevier
Mast cells, accumulate in the stroma surrounding certain tumors and take part to the
inflammatory reaction occurring at the periphery of the tumor. Mast cell-secreted angiogenic …

The prognostic significance of non-lymphoid immune cells of the tumor microenvironment, including neutrophils, eosinophils, and mast cells in breast carcinomas

O Okcu, Ç Öztürk, B Şen, MS Ayazoğlu… - Annals of diagnostic …, 2023 - Elsevier
Background and objective The prognostic importance of lymphoid cells in the tumor
microenvironment and their effect on treatment response have been demonstrated in many …

Optoacoustic breast imaging: imaging-pathology correlation of optoacoustic features in benign and malignant breast masses

R Butler, PT Lavin, FL Tucker… - American Journal of …, 2018 - Am Roentgen Ray Soc
OBJECTIVE. Optoacoustic ultrasound breast imaging is a fused anatomic and functional
modality that shows morphologic features, as well as hemoglobin amount and relative …