There is a growing interest in using natural medicines to treat stroke as the leading cause of
disability worldwide. Especially plant-derived natural medicines have multiple beneficial …

Natural products are an important source of new drugs for the treatment of various diseases.
However, developing natural product-based new medicines through random moiety …

Ferroptosis is a form of regulated cell death, characterized by excessive membrane lipid
peroxidation in an iron-and ROS-dependent manner. Celastrol, a natural bioactive …

Background: Oxidative stress from elevated reactive oxygen species (ROS) has been
reported to induce cell apoptosis and may provide a means to target cancer cells. Celastrol …

As a terpenoids natural product isolated from the plant Thunder God Vine, Celastrol is
widely studied for its pharmacological activities, including anti-tumor activities. The clinical …

As the COVID-19 pandemic is progressing, the therapeutic gaps in conventional
management have highlighted the need for the integration of traditional knowledge systems …

Covering: 2000 to 2020 Triptolide is a bioactive diterpene triepoxide isolated from
Tripterygium wilfordii Hook F, a traditional Chinese medicinal plant whose extracts have …

Triptolide and celastrol are predominantly active natural products isolated from the
medicinal plant Tripterygium wilfordii Hook F. These compounds exhibit similar …

Spinal cord injury (SCI) is a neurological disorder associated with the loss of sensory and
motor function. Understanding the precise dysregulated signaling pathways, especially …

In the past decades, triptolide has attracted considerable interests in the organic and
medicinal chemistry society owing to its intriguing structure features and promising multiple …