Phages are the most abundant and diverse biological entities on Earth and exert specific
effects on bacterial hosts. The coexistence of phages and bacteria in the intestinal tract is …

Foodborne illnesses continue to have an economic impact on global health care systems.
There is a growing concern regarding the increasing frequency of antibiotic resistance in …

The importance of the microbiome to human health is increasingly recognized and has
become a major focus of recent research. However, much of the work has focused on a few …

Bacteriophages are the predominant biological entity on the planet. The recent explosion of
sequence information has made estimates of their diversity possible. We describe the …

Horizontal gene transfer (HGT) can create tremendous genetic diversity in organisms,
especially those which reproduce asexually. The three classical mechanisms for HGT in …

Highlights•The foundations of the antibiotic resistome were laid long before the introduction
of antibiotics into clinical practice.•Here, we update our theoretical framework for the …

Antibiotic resistance is a worldwide health risk, but the influence of animal agriculture on the
genetic context and enrichment of individual antibiotic resistance alleles remains unclear …

An estimated 1.3 million Salmonella infections and 420 deaths occur annually in the United
States, with an estimated economic burden of $3.7 billion. More than 50% of US swine …

Bacteriophages are viruses that infect bacteria. There are an estimated 1031 phage on the
planet, making them the most abundant form of life. We are rapidly approaching the …

The emergence and spread of antimicrobial resistance (AMR) among pathogenic bacteria
constitute an accelerating crisis for public health. The selective pressures caused by …