Goal: This work presents the development of a Hybrid Mock Circulatory Loop (HMCL) to
simulate hemodynamics at patient-specific level in terms of both 3D geometry and …

Vascular disease is the leading cause of morbidity and mortality and a major cause of
disability for Americans, and arterial stenosis is its most common form in systemic arteries …

Abstract Tetralogy of Fallot (ToF) is the most common congenital heart disease. In this work,
hemodynamics of pulmonary arteries (PA) in ToF patients was investigated using patient …

Introduction: Patient-specific computational models are a powerful tool for planning
cardiovascular interventions. However, the in vivo patient-specific mechanical properties of …

Thoracic aortic aneurysms (TAAs) are commonly seen in cardiovascular practice. Acquired
and genetic conditions contribute to TAA formation. The natural history of genetically …

Current biomedical research relies primarily on in silico studies to model complex systems
like cardiovascular hemodynamics. However, for comprehensive validation of mathematical …

Background Abdominal Aortic Aneurysm (AAA) is a balloon-like dilatation that can be life-
threatening if not treated. Fabricating patient-specific AAA models can be beneficial for in …

Emerging treatments for tricuspid valve (TV) regurgitation require realistic TV pathological
models for preclinical testing. The aim of this work was to investigate structural features of …

Background Cardiovascular diseases remain a leading cause of morbidity and mortality
worldwide and require extensive investigation through in-vitro studies. Mock Circulatory …

Introduction Three-dimensional printed models are widely used in the medical field for
surgical and interventional planning. In the context of complex cardiovascular defects such …