Hepatorenal syndrome (HRS), the extreme manifestation of renal impairment in patients with
cirrhosis, is characterized by reduction in renal blood flow and glomerular filtration rate …

Renal dysfunction is a common, life-threatening complication occurring in patients with liver
disease. Hepatorenal syndrome (HRS) has been defined as a purely “functional” type of …

This AASLD Guidance provides a data-supported approach to the management of ascites
and HRS. It differs from the AASLD Guidelines, which are supported by systematic reviews …

The pathophysiological background of decompensated cirrhosis is characterised by a
systemic proinflammatory and pro-oxidant milieu that plays a major role in the development …

The term acute-on-chronic liver failure (ACLF) defines an abrupt and life-threatening
worsening of clinical conditions in patients with cirrhosis or chronic liver disease. In recent …

The peripheral arterial vasodilation hypothesis has been most influential in the field of
cirrhosis and its complications. It has given rise to hundreds of pathophysiological studies in …

Non-alcoholic fatty liver disease (NAFLD) has become one of the most frequent chronic liver
diseases in the Western society and its prevalence is likely to rise even further. An …

Background & Aims We investigated the effect of albumin treatment (20% solution) on
hypoalbuminemia, cardiocirculatory dysfunction, portal hypertension, and systemic …

Human serum albumin (HSA) is one of the most frequent treatments in patients with
decompensated cirrhosis. Prevention of paracentesis-induced circulatory dysfunction …

Patients with acutely decompensated cirrhosis have a dismal prognosis and frequently
progress to acute-on-chronic liver failure, which is characterised by hepatic and extrahepatic …