The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …

Background: Contemporary data are needed about the utility of cannabinoids in chronic
pain. Purpose: To evaluate the benefits and harms of cannabinoids for chronic pain. Data …

The management of orofacial pain to alleviate the quality of life of affected patients is
becoming increasingly challenging for scientific research and healthcare professionals …

Summary Δ 9-tetrahydrocannabinol (THC) and its sibling, cannabidiol (CBD), are produced
by the same Cannabis plant and have similar chemical structures but differ dramatically in …

We report a systematic review and meta-analysis of studies that assessed the
antinociceptive efficacy of cannabinoids, cannabis-based medicines, and endocannabinoid …

Cannabidiol (CBD) is increasingly used as analgesic medication although the recent
International Association for the Study of Pain Presidential Task Force on cannabis and …

Neuropathic pain represents a broad category of pain syndromes that include a wide variety
of peripheral and central disorders. The overall prevalence of neuropathic pain in the …

Background and Purpose Cannabinoids are a promising therapeutic avenue for chronic
pain. However, clinical trials often fail to report analgesic efficacy of cannabinoids. Inhibition …

Abstract Coptis Chinensis Franch is widely used in the treatment of diabetes, and berberine
is the primary bioactive component in it. Evidence from previous studies has shown that …

The endocannabinoids are lipid-derived messengers that play a diversity of regulatory roles
in mammalian physiology. Dysfunctions in their activity have been implicated in various …