High-throughput relative quantification of fatty acids by 12-plex isobaric labeling and microchip capillary electrophoresis-Mass spectrometry

Z Wang, M Li, S Xu, L Sun, L Li - Analytica Chimica Acta, 2024 - Elsevier
Abstract Background Fatty acids (FAs) are essential cellular components and play important
roles in various biological processes. Importantly, FAs produced by microorganisms from …

6-Plex mdSUGAR Isobaric-Labeling Guide Fingerprint Embedding for Glycomics Analysis

M Ma, M Li, Y Zhu, Y Zhao, F Wu, Z Wang… - Analytical …, 2023 - ACS Publications
Glycans are vital biomolecules with diverse functions in biological processes. Mass
spectrometry (MS) has become the most widely employed technology for glycomics studies …

Development of novel isobaric tags enables accurate and sensitive multiplexed proteomics using complementary ions

M Li, M Ma, L Li - Analytical and bioanalytical chemistry, 2023 - Springer
High-throughput quantitative analysis of the cells' proteomes across multiple conditions such
as various perturbations and different time points is essential for gaining insights into …

Standards-Free Absolute Quantitation of Oxidizable Glycopeptides by Coulometric Mass Spectrometry

KY Chiu, Y Ai, M Tanim-AI Hassan, X Li… - Journal of the …, 2024 - ACS Publications
Currently, glycopeptide quantitation is mainly based on relative quantitation due to absolute
quantitation requiring isotope-labeled or standard glycopeptides which may not be …

The role of clinical glyco (proteo) mics in precision medicine

Y van der Burgt, M Wuhrer - Molecular & Cellular Proteomics, 2023 - ASBMB
Glycoproteomics reveals site-specific O-and N-glycosylation that may influence protein
properties including binding, activity, and half-life. The increasingly mature toolbox with …

A Multipoint Validation of Quantification in Capillary Electrophoresis Mass Spectrometry Proteomics: Isobaric Multiplexing with Tandem Mass Tags

L Rodriguez, C Lombard-Banek, V Quach, S Choi… - 2024 - chemrxiv.org
Multiplexing quantification using isobaric barcoding has gained traction in single-cell mass
spectrometry (MS), both in nano-flow liquid chromatography (nanoLC) and capillary …