Controlled droplet microfluidic systems for multistep chemical and biological assays

TS Kaminski, P Garstecki - Chemical Society Reviews, 2017 - pubs.rsc.org
Droplet microfluidics is a relatively new and rapidly evolving field of science focused on
studying the hydrodynamics and properties of biphasic flows at the microscale, and on the …

Engineering compartmentalized biomimetic micro-and nanocontainers

T Trantidou, M Friddin, Y Elani, NJ Brooks, RV Law… - Acs Nano, 2017 - ACS Publications
Compartmentalization of biological content and function is a key architectural feature in
biology, where membrane bound micro-and nanocompartments are used for performing a …

Droplet microfluidics for the construction of compartmentalised model membranes

T Trantidou, MS Friddin, A Salehi-Reyhani, O Ces… - Lab on a Chip, 2018 - pubs.rsc.org
The design of membrane-based constructs with multiple compartments is of increasing
importance given their potential applications as microreactors, as artificial cells in synthetic …

Droplet microfluidics for synthetic biology

PC Gach, K Iwai, PW Kim, NJ Hillson, AK Singh - Lab on a Chip, 2017 - pubs.rsc.org
Synthetic biology is an interdisciplinary field that aims to engineer biological systems for
useful purposes. Organism engineering often requires the optimization of individual genes …

Artificial cell membrane systems for biosensing applications

T Osaki, S Takeuchi - Analytical chemistry, 2017 - ACS Publications
Biological membranes provide a physical boundary that separates the inside and outside of
a cell or organelle. They also mediate signal transduction and transport of various molecules …

Membrane protein-based biosensors

N Misawa, T Osaki, S Takeuchi - Journal of the Royal …, 2018 - royalsocietypublishing.org
This review highlights recent development of biosensors that use the functions of membrane
proteins. Membrane proteins are essential components of biological membranes and have a …

Functional aqueous droplet networks

MJ Booth, VR Schild, FG Downs, H Bayley - Molecular BioSystems, 2017 - pubs.rsc.org
Droplet interface bilayers (DIBs), comprising individual lipid bilayers between pairs of
aqueous droplets in an oil, are proving to be a useful tool for studying membrane proteins …

Challenges and opportunities in achieving the full potential of droplet interface bilayers

EB Stephenson, JL Korner, KS Elvira - Nature Chemistry, 2022 - nature.com
Abstract Model membranes can be used to elucidate the intricacies of the chemical
processes that occur in cell membranes, but the perfectly biomimetic, yet bespoke, model …

Droplet-interface-bilayer assays in microfluidic passive networks

B Schlicht, M Zagnoni - Scientific reports, 2015 - nature.com
Basic biophysical studies and pharmacological processes can be investigated by mimicking
the intracellular and extracellular environments across an artificial cell membrane construct …

Characterisation of cell membrane interaction mechanisms of antimicrobial peptides by electrical bilayer recording

D Priyadarshini, J Ivica, F Separovic… - Biophysical …, 2022 - Elsevier
Many antimicrobial peptides (AMPs) are cationic host defence peptides (HDPs) that interact
with microbial membranes. This ability may lead to implementation of AMPs as therapeutics …