The interactions among tumour cells, the tumour microenvironment (TME) and non-tumour
tissues are of interest to many cancer researchers. Micro-engineering approaches and …

This review describes recent research that has advanced our understanding of the role of
immune cells in the tumor microenvironment (TME) using advanced 3D in vitro models and …

Inflammatory breast cancer (IBC), the most aggressive breast cancer subtype, is driven by
an immunosuppressive tumor microenvironment (TME). Current treatments for IBC have …

Purpose To determine the role of macrophage polarization on the response of inflammatory
breast cancer (IBC) cells to radiation and whether modulation of macrophage plasticity can …

The advances in cancer immunotherapy come with several obstacles, limiting its
widespread use and benefits so far only to a small subset of patients. One of the underlying …

Abstract Background Tumor-associated macrophages (TAMs) are associated with poor
outcomes in multiple solid cancers and play important roles in cancer progression. Epithelial …

Cancer immunotherapy is fast rising as a prominent new pillar of cancer treatment,
harnessing the immune system to fight against numerous types of cancer. Rho-kinase …

Tumor associated macrophages (TAMs) are increasingly recognized as major contributors
to the metastatic progression of breast cancer and enriched levels of TAMs often correlate …

Metabolic flux technology with the Seahorse bioanalyzer has emerged as a standard
technique in cellular metabolism studies, allowing for simultaneous kinetic measurements of …

Inflammatory breast cancer (IBC) is the most rare and aggressive subtype of breast cancer
characterized by clusters of tumor cells invading lymph vessels, high rates of metastasis …