Vasculopathy in sickle cell disease: from red blood cell sickling to vascular dysfunction

E Nader, N Conran, M Romana… - Comprehensive …, 2011 - Wiley Online Library
Sickle cell disease (SCD) is a hereditary disorder that leads to the production of an
abnormal hemoglobin, hemoglobin S (HbS). HbS polymerizes in deoxygenated conditions …

Non-hematopoietic deficiency of proprotein convertase subtilisin/kexin type 9 deficiency leads to more severe anemia in a murine model of sickle cell disease

J Venugopal, J Wang, C Guo, H Lu, YE Chen… - Scientific Reports, 2020 - nature.com
Proprotein convertase subtilisin/kexin type 9 (PCSK9) deficiency leads to lower cholesterol
and is associated with reduced vascular complications in the general population …

[PDF][PDF] Pain Management in Sickle Cell Disease

A Alwaheed, MB Essa - 2019 - repositorium.meduniwien.ac.at
Abstract Sickle Cell Disease (SCD) is a genetically transmitted red cell disorder, which
affects the shape of haemoglobin, a protein in red blood cell (RBC) obstructing blood flow …

[PDF][PDF] EFFECT OF METFORMIN AND ROSUVASTATIN ON ERYTHROCYTES OF PATIENTS WITH SICKLE CELL DISEASE: AN IN-VITRO STUDY

SF Abbas, JH Ahmed - researchgate.net
Objectives: Sickle cell disease (SCD) is a common hereditary blood disease with a
progressive clinical course and multiple end organs damage. Due to its intercalated …

[引用][C] Determination of Lipid Metabolism Alterations and Their Association with Disease Pathogenesis in Sickle Cell Disease

A Yalçınkaya - 2020 - Sağlık Bilimleri Enstitüsü