Membrane proteomics by high performance liquid chromatography–tandem mass spectrometry: Analytical approaches and challenges

D Vuckovic, LF Dagley, AW Purcell, A Emili - Proteomics, 2013 - Wiley Online Library
Membrane proteins (MP s) play diverse biologically important structural and functional roles
including molecular transport, cell communication, and signal transduction. The dysfunctions …

Mass spectrometry and the cellular surfaceome

J Pauwels, D Fijałkowska, S Eyckerman… - Mass spectrometry …, 2022 - Wiley Online Library
The collection of exposed plasma membrane proteins, collectively termed the surfaceome, is
involved in multiple vital cellular processes, such as the communication of cells with their …

Detailed analysis of protein topology of extracellular vesicles–evidence of unconventional membrane protein orientation

A Cvjetkovic, SC Jang, B Konečná, JL Höög… - Scientific reports, 2016 - nature.com
Extracellular vesicles (EVs) are important mediators of intercellular communication that
change the recipient cell by shuttling lipids, RNA, or protein cargo between cells. Here, we …

[HTML][HTML] Red cell investigations: art and artefacts

G Minetti, S Egée, D Mörsdorf, P Steffen, A Makhro… - Blood reviews, 2013 - Elsevier
Red blood cell research is important for both, the clinical haematology, such as transfusion
medicine or anaemia investigations, and the basic research fields like exploring general …

PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein

M Thura, AQ Al-Aidaroos, A Gupta, CE Chee… - Nature …, 2019 - nature.com
Tumor-specific antibody drugs can serve as cancer therapy with minimal side effects. A
humanized antibody, PRL3-zumab, specifically binds to an intracellular oncogenic …

Recent advances in multidimensional separation for proteome analysis

H Yuan, B Jiang, B Zhao, L Zhang, Y Zhang - Analytical Chemistry, 2018 - ACS Publications
Proteome was first coined by describing the set of proteins encoded by the genome, and the
study of proteome, named as proteomics, aims at globally characterizing all components in a …

The proteomics and interactomics of human erythrocytes

SR Goodman, O Daescu… - Experimental …, 2013 - journals.sagepub.com
In this minireview, we focus on advances in our knowledge of the human erythrocyte
proteome and interactome that have occurred since our seminal review on the topic …

Protein-Cloaked Nanoparticles for Enhanced Cellular Association and Controlled Pathophysiology via Immunosurveillance Escape

AI Dar, SMS Abidi, S Randhawa, R Joshi… - … Applied Materials & …, 2021 - ACS Publications
Weak interactions play an important role in soft corona (SC) formation and thus help in
evaluating the biological fate of the nanoparticles (NPs). Preadsorption of specific proteins …

Shotgun protein profile of human adipose tissue and its changes in relation to systemic amyloidoses

F Brambilla, F Lavatelli, D Di Silvestre… - Journal of proteome …, 2013 - ACS Publications
In systemic amyloidosis, accumulation of misfolded proteins as extracellular amyloid fibrils in
tissues causes severe organ dysfunction, but the molecular events of tissue damage related …

A label-free proteome analysis strategy for identifying quantitative changes in erythrocyte membranes induced by red cell disorders

EN Pesciotta, S Sriswasdi, HY Tang, PJ Mason… - Journal of …, 2012 - Elsevier
Red blood cells have been extensively studied but many questions regarding membrane
properties and pathophysiology remain unanswered. Proteome analysis of red cell …