The skeletal muscle extracellular matrix (ECM) plays an important role in muscle fiber force
transmission, maintenance, and repair. In both injured and diseased states, ECM adapts …

Skeletal muscles are length-and velocity-sensitive force producers, constructed of a vast
array of sarcomeres. Muscles come in a variety of sizes and shapes to accomplish a wide …

Non‐technical summary Muscle spasticity, due to an upper motoneuron lesion, often leads
to muscle contractures that limit range of motion and cause increased muscle stiffness …

A new musculoskeletal model for the lumbar spine is described in this paper. This model
features a rigid pelvis and sacrum, the five lumbar vertebrae, and a rigid torso consisting of a …

The following papers by Richard Lieber (Skeletal Muscle as an Actuator), Thomas Roberts
(Elastic Mechanisms and Muscle Function), Silvia Blemker (Skeletal Muscle has a Mind of its …

In vitro models of skeletal muscle are critically needed to elucidate disease mechanisms,
identify therapeutic targets and test drugs pre-clinically. However, culturing skeletal muscle …

Skeletal muscle has the remarkable ability to remodel and adapt, such as the increase in
serial sarcomere number (SSN) or fascicle length (FL) observed after overstretching a …

Key points The amount of fibrotic material in dystrophic mouse muscles relates to contractile
function, but not passive function. Collagen fibres in skeletal muscle are associated with …

Back pain (BP) is a common condition of major social importance and poorly understood
pathogenesis. Combining data from the UK Biobank and CHARGE consortium cohorts …

Many skeletal muscle diseases are associated with progressive fibrosis leading to impaired
muscle function. Collagen within the extracellular matrix is the primary structural protein …