This review discusses various issues to consider when developing standard operating
procedures for pre-clinical studies in the mdx mouse model of Duchenne muscular …

Dystrophinopaties, eg, Duchenne muscular dystrophy (DMD), Becker muscular dystrophy
and X-linked dilated cardiomyopathy are inherited neuromuscular diseases, characterized …

Background Alzheimer's disease (AD) is characterized by a neurodegenerative progression
that alters cognition. On a phenotypical level, cognition is evaluated by means of the …

Mice lacking the sarcolemmal protein dystrophin, designated mdx, have been widely used
as a model of Duchenne muscular dystrophy. Dystrophic mdx mice as they mature develop …

Duchenne muscular dystrophy (DMD) is the most common and relentless form of muscular
dystrophy. The pleiotropic effects of dystrophin deficiency include remarkable impacts on …

Duchenne muscular dystrophy (DMD) is characterized by muscle degeneration and
structural defects in the neuromuscular synapse that are caused by mutations in dystrophin …

Duchenne muscular dystrophy (DMD) is a fatal muscle wasting disorder caused by
mutations in the dystrophin gene. DMD has a complex and as yet incompletely defined …

Denervation leads to severe atrophy of neuromuscular junction (NMJ) structure including
decrease of the expression of fundamental proteins. Up to now, conventional suture has …

Duchenne muscular dystrophy (DMD) is the most severe and frequent form of muscular
dystrophy. The mdx mouse is one of the most widely used experimental models to …

The muscle fiber phenotype is mainly determined by motoneuron innervation and changes
in neuromuscular interaction alter the muscle fiber type. In dystrophin‐deficient mdx mice …