Von Willebrand's disease is the most common inherited bleeding disorder and is generally
transmitted as an autosomal dominant trait. It is mainly associated with mucosal bleeding …

Essentials• The optimal management of patients with platelet dysfunction undergoing
surgery is unclear.• This meta‐analysis compared perioperative administration of …

The management of perioperative bleeding involves multiple assessments and strategies to
ensure appropriate patient care. Initially, it is important to identify those patients with an …

Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

This report presents the recommendations of the WHO Expert Committee responsible for
updating the WHO Model Lists of Essential Medicines.. The goal of the meeting was to …

The management of von Willebrand disease (VWD) is based upon the dual correction of the
primary hemostasis defect, due to the inherited deficiency of von Willebrand factor (VWF) …

Von Willebrand disease (VWD) constitutes the most common inherited human bleeding
disorder. It is associated with a mucocutaneous bleeding phenotype that can significantly …

Introduction: Desmopressin is frequently used in patients with bleeding disorders because of
its prohaemostatic effects. In recent years desmopressin use increased due to reported high …

Background Although desmopressin (DDAVP) is an accessible and inexpensive hemostatic
drug, its use in pregnancy is still debated due to safety uncertainties. Objectives We aimed to …

Type 2B von Willebrand disease (VWD) is an inherited bleeding disorder caused by
changes in von Willebrand factor (VWF) that enhance binding of VWF to GPIb on platelets …