The most common cause of acquired thyroid dysfunction is autoimmune thyroid disease,
which is an organ-specific autoimmune disease with two presentation phenotypes …

Graves' disease is the most frequent cause of hyperthyroidism. Many questions remain
about the choice of diagnostic evaluations and treatment strategy according to clinical …

We have genotyped 14,436 nonsynonymous SNPs (nsSNPs) and 897 major
histocompatibility complex (MHC) tag SNPs from 1,000 independent cases of ankylosing …

BACKGROUND: Common autoimmune disorders tend to coexist in the same subjects and to
cluster in families. METHODS: We performed a cross-sectional multicenter study of 3286 …

Context: Both genetic and environmental factors contribute to susceptibility to Graves'
disease (GD) and Hashimoto's thyroiditis (HT), as well as disease manifestations. Objective …

Discovery of a large family of Fc receptor-like (FCRL) molecules, homologous to the well-
known receptors for the Fc portion of immunoglobulin (FCR), has uncovered an impressive …

In spite of the advancements in understanding the pathogenic mechanisms of Graves'
disease (GD), its ultimate cause remains elusive. The majority of investigators agree that GD …

OBJECTIVE In contrast with childhood-onset type 1 diabetes, the genetics of autoimmune
diabetes in adults are not well understood. We have therefore investigated the genetics of …

The immunologic processes involved in autoimmune thyroid disease (AITD), particularly
Graves' disease (GD), are similar to other autoimmune diseases with the emphasis on the …

The ability of the immune system to protect the body from attack by foreign antigens is
essential for human survival. The immune system can, however, start to attack the body's …