Self-grooming is a complex innate behaviour with an evolutionarily conserved sequencing
pattern and is one of the most frequently performed behavioural activities in rodents. In this …

Clinical–pathological studies remain the gold‐standard for the diagnosis of Parkinson's
disease (PD). However, mounting data from genetic PD autopsies challenge the diagnosis …

Parkinson's disease (PD) is the second most common neurodegenerative disorder and the
fastest growing neurologic disease in the world, yet no disease-modifying therapy is …

Almost two decades of genetic research in Parkinson's disease (PD) have remarkably
increased our knowledge regarding the genetic basis of PD with numerous genes and …

The recent formalization of clinical criteria for Parkinson's disease with dementia (PDD)
codifies many studies on this topic, including those assessing biological correlates. These …

The cause of Parkinson's disease (PD) remains unknown in most patients. Since 1997, with
the first genetic mutation known to cause PD described in SNCA gene, many other genes …

This comprehensive MDSGene review is devoted to the three autosomal‐dominant PD
forms: PARK‐SNCA, PARK‐LRRK2, and PARK‐VPS35. It follows MDSGene's standardized …

Cognitive impairment is a common non-motor symptom in Parkinson's Disease (PD) and an
important source of patient disability and caregiver burden. The timing, profile and rate of …

Mutations in the GBA1 gene are the most common genetic risk factor for Parkinson's disease
(PD) and dementia with Lewy bodies (DLB). GBA1 encodes the lysosomal lipid hydrolase …

In a number of neurological diseases including Parkinson's disease (PD), α‑synuclein is
aberrantly folded, forming abnormal oligomers, and amyloid fibrils within nerve cells. Strong …