Revisiting the dimensions of universal vaccine with special focus on COVID-19: Efficacy versus methods of designing

P Jaishwal, K Jha, SP Singh - International Journal of Biological …, 2024 - Elsevier
Even though the use of SARS-CoV-2 vaccines during the COVID-19 pandemic showed
unprecedented success in a short time, it also exposed a flaw in the current vaccine design …

Efficient and stable production of Modified Vaccinia Ankara virus in two-stage semi-continuous and in continuous stirred tank cultivation systems

F Tapia, I Jordan, Y Genzel, U Reichl - PLoS One, 2017 - journals.plos.org
One important aim in cell culture-based viral vaccine and vector production is the
implementation of continuous processes. Such a development has the potential to reduce …

Deletion of vaccinia virus A40R gene improves the immunogenicity of the HIV-1 vaccine candidate MVA-B

P Pérez, MQ Marín, A Lázaro-Frías, CÓS Sorzano… - Vaccines, 2020 - mdpi.com
Development of a safe and efficacious vaccine against the HIV/AIDS pandemic remains a
major scientific goal. We previously described an HIV/AIDS vaccine based on the modified …

A Prime/Boost PfCS14KM/MVA-sPfCSM Vaccination Protocol Generates Robust CD8+ T Cell and Antibody Responses to Plasmodium falciparum Circumsporozoite …

A Vijayan, E Mejías-Pérez, DA Espinosa… - Clinical and Vaccine …, 2017 - Am Soc Microbiol
Vaccines against the preerythrocytic stages of malaria are appealing because the parasite
can be eliminated before disease onset and because they offer the unique possibility of …

Анализ и перспективы применения рекомбинантного вируса вакцины, штамм MVA, в качестве вектора при разработке вакцин против заболеваний …

ЛФ Стовба, ВТ Кротков, ДИ Павельев… - Проблемы особо …, 2019 - cyberleninka.ru
В обзоре представлены результаты доклинического применения векторных вакцин
против заболеваний, вызванных вирусами иммунодефицита человека и …

[PDF][PDF] HIV-1 Env 三聚体抗原改造研究进展

沈鸿霖, 张芝晴, 李少伟, 顾颖 - Chin J Biotech, 2019 - core.ac.uk
HIV-1 疫苗研发是当前艾滋病研究的一大热点, 其病毒表面包膜糖蛋白Env
三聚体介导病毒与细胞融合, 是HIV-1 疫苗研究的重要靶点. 因此, 设计并在体外表达类天然Env …

The Envelope-Based Fusion Antigen GP120C14K Forming Hexamer-Like Structures Triggers T Cell and Neutralizing Antibody Responses Against HIV-1

SC Raman, E Mejías-Pérez, CE Gomez… - Frontiers in …, 2019 - frontiersin.org
There is an urgent need for the development of potent vaccination regimens that are able to
induce specific T and B cell responses against human immunodeficiency virus type 1 (HIV …

Deletion of Vaccinia Virus A40R Gene Improves the Immunogenicity of the HIV-1 Vaccine Candidate MVA-B

P Pérez Ramírez, MQ Marín, A Lázaro-Frías… - 2020 - digital.csic.es
Development of a safe and efficacious vaccine against the HIV/AIDS pandemic remains a
major scientific goal. We previously described an HIV/AIDS vaccine based on the modified …

[PDF][PDF] Science Repository

A Sousa - 2020 - pdfs.semanticscholar.org
The COVID-19 pandemic has become the most serious health problem of the 21st century.
Knowing whether its origin was natural or artificial is an extremely important fact, especially …

[PDF][PDF] Continuous upstream processing for cell culture-derived virus production

F Tapia - 2019 - pure.mpg.de
Viral vaccines are one of the most successful medical developments in human history. Since
their introduction in the global health system, the average human life span and the …