Schizophrenia risk has often been conceptualized using a model which requires two hits in
order to generate the clinical phenotype—the first as an early priming in a genetically …

Diseases diagnosed in adulthood may have antecedents throughout (including prenatal)
life. Gaining a better understanding of how exposures at different stages in the lifecourse …

Maternal smoking during pregnancy has been found to influence newborn DNA methylation
in genes involved in fundamental developmental processes. It is pertinent to understand the …

ARIES is a population-based resource of DNA methylation data accessible by the research
community, established with the aim of improving our understanding of the determinants and …

Prenatal adverse environments, such as maternal stress, toxicological exposures, and viral
infections, can disrupt normal brain development and contribute to neurodevelopmental …

Neurodevelopmental diseases (NDDs), such as autism spectrum disorders, epilepsy, and
schizophrenia, are characterized by diverse facets of neurological and psychiatric …

Folate plays a key role in the interactions between nutrition, fetal programming, and
epigenomics. Maternal folate status influences DNA methylation, inheritance of the agouti …

Neuropsychiatric disorders, such as autism spectrum disorder (ASD), attention deficit
hyperactivity disorder (ADHD), schizophrenia (SCZ), bipolar disorder (BIP), and major …

The pathogenesis of schizophrenia is considered to be multi-factorial, with likely gene–
environment interactions (GEI). Genetic and environmental risk factors are being identified …

The molecular basis for the majority of cases of autism spectrum disorders (ASD) remains
unknown. We tested the hypothesis that ASD have an epigenetic cause by performing DNA …