Molecular genetics and emerging therapies for retinitis pigmentosa: Basic research and clinical perspectives
MF Dias, K Joo, JA Kemp, SL Fialho… - Progress in retinal and …, 2018 - Elsevier
Retinitis Pigmentosa (RP) is a hereditary retinopathy that affects about 2.5 million people
worldwide. It is characterized with progressive loss of rods and cones and causes severe …
worldwide. It is characterized with progressive loss of rods and cones and causes severe …
Ocular neurodegenerative diseases: interconnection between retina and cortical areas
The possible interconnection between the eye and central nervous system (CNS) has been
a topic of discussion for several years just based on fact that the eye is properly considered …
a topic of discussion for several years just based on fact that the eye is properly considered …
Chemistry of the retinoid (visual) cycle
As succinctly summarized by Wolf, 1 lack of vitamin A (all-trans-retinol) was recognized by
ancient Egyptians as causing a visual deficiency involving the retina and cornea that could …
ancient Egyptians as causing a visual deficiency involving the retina and cornea that could …
[HTML][HTML] Long-term results from an epiretinal prosthesis to restore sight to the blind
Purpose Retinitis pigmentosa (RP) is a group of inherited retinal degenerations leading to
blindness due to photoreceptor loss. Retinitis pigmentosa is a rare disease, affecting only …
blindness due to photoreceptor loss. Retinitis pigmentosa is a rare disease, affecting only …
Microglia modulation by TGF-β1 protects cones in mouse models of retinal degeneration
Retinitis pigmentosa (RP) is a genetically heterogenous group of eye diseases in which
initial degeneration of rods triggers secondary degeneration of cones, leading to significant …
initial degeneration of rods triggers secondary degeneration of cones, leading to significant …
Pharmacological approaches to retinitis pigmentosa: a laboratory perspective
Retinal photoreceptors are highly specialized and performing neurons. Their cellular
architecture is exquisitely designed to host a high concentration of molecules involved in …
architecture is exquisitely designed to host a high concentration of molecules involved in …
Neuroprotective effects of FGF2 and minocycline in two animal models of inherited retinal degeneration
J Di Pierdomenico, R Scholz… - … & visual science, 2018 - iovs.arvojournals.org
Purpose: The purpose of this study was to study the effect of minocycline and several
neurotrophic factors, alone or in combination, on photoreceptor survival and …
neurotrophic factors, alone or in combination, on photoreceptor survival and …
Autophagy dysfunction and oxidative stress, two related mechanisms implicated in retinitis pigmentosa
ML Moreno, S Mérida, F Bosch-Morell… - Frontiers in …, 2018 - frontiersin.org
Retinitis pigmentosa (RP) is one of the most common clinical subtypes of retinal
degeneration (RD), and it is a neurodegenerative disease that could cause complete …
degeneration (RD), and it is a neurodegenerative disease that could cause complete …
Delay of cone degeneration in retinitis pigmentosa using a 12-month treatment with Lycium barbarum supplement
Ethnopharmacological relevance Lycium barbarum L.(also known as “Goji berry”), a
traditional Chinese herbal medicine, has been a common herb in the traditional Chinese …
traditional Chinese herbal medicine, has been a common herb in the traditional Chinese …
Nanocarriers for the delivery of neuroprotective agents in the treatment of ocular neurodegenerative diseases
Retinal neurodegeneration is considered an early event in the pathogenesis of several
ocular diseases, such as diabetic retinopathy, age-related macular degeneration, and …
ocular diseases, such as diabetic retinopathy, age-related macular degeneration, and …