The bioactive peptides galanin, spexin and kisspeptin have a common ancestral origin and
their pathophysiological roles are increasingly the subject of investigation. Evidence …

Reproductive hormones play a crucial role in the growth and maintenance of the
mammalian skeleton. Indeed, the biological significance for this hormonal regulation of …

Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …

In late 2003, a major breakthrough in our understanding of the mechanisms that govern
reproduction occurred with the identification of the reproductive roles of kisspeptins …

Importance Despite being the most common female sexual health complaint worldwide,
current treatment options for hypoactive sexual desire disorder (HSDD) are limited in their …

Nitric oxide (NO) is a versatile molecule that plays key roles in the development and survival
of mammalian species by endowing brain neuronal networks with the ability to make …

Background: Two major constituents of cannabis are Δ9-tetrahydrocannabinol (THC) and
cannabidiol (CBD). THC is the main psychoactive component; CBD may buffer the user …

BACKGROUND Hypoactive sexual desire disorder (HSDD) is characterized by a persistent
deficiency of sexual fantasies and desire for sexual activity, causing marked distress and …

OBJECTIVE Weight loss achieved with very-low-calorie diets (VLCDs) can produce
remission of type 2 diabetes (T2D), but weight regain very often occurs with reintroduction of …

Importance The human physiological sexual response is crucial for reward, satisfaction, and
reproduction. Disruption of the associated neurophysiological pathways predisposes to low …