Acute respiratory distress syndrome

MA Matthay, RL Zemans, GA Zimmerman… - Nature reviews Disease …, 2019 - nature.com
The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

The acute respiratory distress syndrome

MA Matthay, LB Ware… - The Journal of clinical …, 2012 - Am Soc Clin Investig
The acute respiratory distress syndrome (ARDS) is an important cause of acute respiratory
failure that is often associated with multiple organ failure. Several clinical disorders can …

Early identification of patients at risk of acute lung injury: evaluation of lung injury prediction score in a multicenter cohort study

O Gajic, O Dabbagh, PK Park, A Adesanya… - American journal of …, 2011 - atsjournals.org
Rationale: Accurate, early identification of patients at risk for developing acute lung injury
(ALI) provides the opportunity to test and implement secondary prevention strategies …

Stem cell conditioned medium improves acute lung injury in mice: in vivo evidence for stem cell paracrine action

L Ionescu, RN Byrne, T van Haaften… - … of Physiology-Lung …, 2012 - journals.physiology.org
Mortality and morbidity of acute lung injury and acute respiratory distress syndrome remain
high because of the lack of pharmacological therapies to prevent injury or promote repair …

Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1

SHJ Mei, SD McCarter, Y Deng, CH Parker… - PLoS …, 2007 - journals.plos.org
Background The acute respiratory distress syndrome (ARDS), a clinical complication of
severe acute lung injury (ALI) in humans, is a leading cause of morbidity and mortality in …

Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management

MA Matthay, GA Zimmerman - American journal of respiratory cell …, 2005 - atsjournals.org
In 2005, the American Thoracic Society marks its 100th year of existence. For over a third of
this span, since 1967, clinicians and investigators have struggled with a common, often …

Sevoflurane for sedation in acute respiratory distress syndrome. A randomized controlled pilot study

M Jabaudon, P Boucher, E Imhoff… - American journal of …, 2017 - atsjournals.org
Rationale: Sevoflurane improves gas exchange, and reduces alveolar edema and
inflammation in preclinical studies of lung injury, but its therapeutic effects have never been …

Pathophysiology of acute lung injury and the acute respiratory distress syndrome

LB Ware - Seminars in respiratory and critical care medicine, 2006 - thieme-connect.com
Since the adult respiratory distress syndrome was first described substantial progress has
been made in understanding the pathogenesis of this complex syndrome. This review …

Transfusion-related acute lung injury in the critically ill: prospective nested case-control study

O Gajic, R Rana, JL Winters, M Yilmaz… - American journal of …, 2007 - atsjournals.org
Rationale: Acute lung injury (ALI) that develops 6 hours after transfusion (TRALI) is the
leading cause of transfusion-related mortality. Several transfusion characteristics have been …

Clinical predictors of and mortality in acute respiratory distress syndrome: potential role of red cell transfusion

MN Gong, BT Thompson, P Williams… - Critical care …, 2005 - journals.lww.com
Objective: Clinical predictors for acute respiratory distress syndrome (ARDS) have been
studied in few prospective studies. Although transfusions are common in the intensive care …