Infectious diseases may affect brain function and cause encephalopathy even when the
pathogen does not directly infect the central nervous system, known as infectious disease …

Sepsis is a systemic inflammatory disease resulting from an infection. This disorder affects
750 000 people annually in the United States and has a 62% rehospitalization rate. Septic …

Coronavirus disease 2019 (COVID-19) is currently a worldwide emergency caused by
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In observational clinical …

Cerebral malaria (CM) caused by Plasmodium falciparum is a fatal neurological
complication of malaria, resulting in coma and death, and even survivors may suffer long …

Zika virus (ZIKV) has been associated to central nervous system (CNS) harm, and virus was
detected in the brain and cerebrospinal fluids of microcephaly and meningoencephalitis …

There is an ongoing threat of epidemic or pandemic diseases that could be caused by
influenza, Ebola or other emerging viruses. It will be difficult and costly to develop new drugs …

Statins not only reduce levels of LDL-cholesterol, they counteract the inflammatory changes
associated with acute coronary syndrome and improve survival. Similarly, in patients …

Sepsis is systemic inflammatory response syndrome with a life-threatening organ
dysfunction that is caused by an unbalanced host immune response in an attempt to …

Sepsis-associated encephalopathy (SAE), a major complication of sepsis, is characterized
by impaired consciousness, including delirium and coma. Additionally SAE associates with …

Sepsis is characterized by inflammatory and metabolic alterations, which lead to massive
cytokine production, oxidative stress and organ dysfunction. In severe systemic inflammatory …