The endothelial angiopoietin (ANG)–TIE growth factor receptor pathway regulates vascular
permeability and pathological vascular remodelling during inflammation, tumour …

Acute pancreatitis (AP) is an inflammatory disease of highly variable severity, ranging from
mild cases with low mortality to severe cases with high mortality. Numerous biomarkers have …

Objective: To develop a new international classification of acute pancreatitis severity on the
basis of a sound conceptual framework, comprehensive review of published evidence, and …

Acute pancreatitis (AP) is an inflammatory disease with varied severity, ranging from mild
local inflammation to severe systemic involvement resulting in substantial mortality. Early …

Acute pancreatitis (AP) is a severe inflammation of the pancreas presented with sudden
onset and severe abdominal pain with a high morbidity and mortality rate, if accompanied by …

Methods This document was prepared by the Standards of Practice Committee of the ASGE
and was conceptualized and conducted according to the Grading of Recommendations …

Background Persistent organ failure and infected pancreatic necrosis are major
determinants of mortality in acute pancreatitis, but there is a gap in the literature assessing …

Acute pancreatitis is a potentially life threatening disease. The spectrum of severity of the
illness ranges from mild self‐limiting disease to a highly fatal severe necrotizing pancreatitis …

Severe acute pancreatitis (SAP) includes persistent systemic inflammation (SIRS) and
multiorgan failure (MOF). The mechanism of transition from SIRS to MOF is unclear. We …

Background: Neutrophil extracellular traps (NETs) are generated when activated
neutrophils, driven by PAD4, release their DNA, histones, HMGB1, and other intracellular …