Radiogenomics: bridging imaging and genomics

Z Bodalal, S Trebeschi, TDL Nguyen-Kim, W Schats… - Abdominal …, 2019 - Springer
From diagnostics to prognosis to response prediction, new applications for radiomics are
rapidly being developed. One of the fastest evolving branches involves linking imaging …

[HTML][HTML] Predicting gene mutation status via artificial intelligence technologies based on multimodal integration (MMI) to advance precision oncology

J Shao, J Ma, Q Zhang, W Li, C Wang - Seminars in cancer biology, 2023 - Elsevier
Personalized treatment strategies for cancer frequently rely on the detection of genetic
alterations which are determined by molecular biology assays. Historically, these processes …

Value of pre-therapy 18F-FDG PET/CT radiomics in predicting EGFR mutation status in patients with non-small cell lung cancer

J Zhang, X Zhao, Y Zhao, J Zhang, Z Zhang… - European journal of …, 2020 - Springer
Purpose To assess the predictive power of pre-therapy 18 F-FDG PET/CT-based radiomic
features for epidermal growth factor receptor (EGFR) mutation status in non-small cell lung …

The application of radiomics in predicting gene mutations in cancer

Y Qi, T Zhao, M Han - European radiology, 2022 - Springer
With the development of genome sequencing, the role of molecular targeted therapy in
cancer is becoming increasingly important. However, genetic testing remains expensive …

Radiogenomic models using machine learning techniques to predict EGFR mutations in non-small cell lung cancer

JKR Nair, UA Saeed, CC McDougall… - Canadian …, 2021 - journals.sagepub.com
Background: The purpose of this study was to build radiogenomics models from texture
signatures derived from computed tomography (CT) and 18F-FDG PET-CT (FDG PET-CT) …

Quantitative CT texture analysis in predicting PD-L1 expression in locally advanced or metastatic NSCLC patients

S Bracci, M Dolciami, C Trobiani, A Izzo, A Pernazza… - La radiologia …, 2021 - Springer
Abstract Purpose The assessment of Programmed death-ligand 1 (PD-L1) expression has
become a game changer in the treatment of patients with advanced non-small cell lung …

Radiomics predicts survival of patients with advanced non‑small cell lung cancer undergoing PD‑1 blockade using Nivolumab

V Nardone, P Tini, P Pastina, C Botta… - Oncology …, 2020 - spandidos-publications.com
Immune checkpoint blockade is an emerging anticancer strategy, and Nivolumab is a
human mAb to PD‑1 that is used in the treatment of a number of different malignancies …

Radiomics signature as a predictive factor for EGFR mutations in advanced lung adenocarcinoma

D Hong, K Xu, L Zhang, X Wan, Y Guo - Frontiers in oncology, 2020 - frontiersin.org
Purpose: To develop and validate a radiomic signature to identify EGFR mutations in
patients with advanced lung adenocarcinoma. Methods: This study involved 201 patients …

Can CT radiomic analysis in NSCLC predict histology and EGFR mutation status?

SR Digumarthy, AM Padole, RL Gullo, LV Sequist… - Medicine, 2019 - journals.lww.com
Can CT radiomic analysis in NSCLC predict histology and EGFR... : Medicine Can CT radiomic
analysis in NSCLC predict histology and EGFR mutation status? : Medicine Log in or Register …

CT-based radiomics for prediction of histologic subtype and metastatic disease in primary malignant lung neoplasms

JR Ferreira-Junior, M Koenigkam-Santos… - International journal of …, 2020 - Springer
Purpose As some of the most important factors for treatment decision of lung cancer (which
is the deadliest neoplasm) are staging and histology, this work aimed to associate …