The exponential increase in published articles makes a thorough and expedient review of
literature increasingly challenging. This review delineated automated tools and platforms …

Polygenic diseases, which are genetic disorders caused by the combined action of multiple
genes, pose unique and significant challenges for the diagnosis and management of …

Abstract Model-based meta-analysis (MBMA) is a quantitative approach that leverages
published summary data along with internal data and can be applied to inform key drug …

Abstract We propose Predict then Interpolate (PI), a simple algorithm for learning
correlations that are stable across environments. The algorithm follows from the intuition that …

Surgeons perform two primary tasks: operating and engaging patients and caregivers in
shared decision-making. Human dexterity and decision-making are biologically limited …

The medical literature has been growing exponentially, and its size has become a barrier for
physicians to locate and extract clinically useful information. As a promising solution, natural …

PURPOSE The medical literature relevant to germline genetics is growing exponentially.
Clinicians need tools that help to monitor and prioritize the literature to understand the …

Natural language processing (NLP) research combines the study of universal principles,
through basic science, with applied science targeting specific use cases and settings …

Purpose Several male breast cancer (MBC) susceptibility genes have been identified, but
the MBC risk for individuals with a pathogenic variant in each of these genes (ie …

Multigene panel testing now allows efficient testing of many cancer susceptibility genes
leading to a larger number of mutation carriers being identified. They need to be counseled …