Old individuals are more susceptible to various infections due to immunological changes
that occur during the aging process. These changes named collectively as …

One of the most appreciated consequences of immunosenescence is an impaired response
to vaccines with advanced age. While most studies report impaired antibody responses in …

Immunosenescence is defined as the progressive deterioration of the immune system with
aging. Immunosenescence stifles the generation of protective B and T cell-mediated …

Infectious diseases are a major cause for morbidity and mortality in the older population.
Demographic changes will lead to increasing numbers of older persons over the next …

The world's population is aging, which brings about huge scientific challenges. Since the
biological process of aging is by far the greatest risk factor for most chronic diseases …

CD4+ T cells play a notable role in immune protection at different stages of life. During
aging, the interaction between the body's internal and external environment and CD4+ T …

Age-related declines in immune response pose a challenge in combating diseases later in
life. Influenza (flu) infection remains a significant burden on older populations and often …

Ageing profoundly changes our immune system and is thought to be a driving factor in the
morbidity and mortality associated with infectious disease in older people. We have …

Objectives This study aimed to assess the burden of early-onset gastrointestinal (GI) cancers
in China over three decades. Study design A comprehensive analysis was performed using …

In the aging process, the presence of interleukin (IL)-17-producing CD4+ CD28-NKG2D+ T
cells (called pathogenic CD4+ T cells) is strongly associated with inflammation and the …