Genetic drugs based on nucleic acid biomolecules are a rapidly emerging class of
medicines that directly reprogramme the central dogma of biology to prevent and treat …

Persistent luminescent phosphors can store light energy in advance and release it with a
long-lasting afterglow emission. With their ability to eliminate in situ excitation and store …

Nanoparticles enter tumours through endothelial cells, gaps or other mechanisms, but how
they exit is unclear. The current paradigm states that collapsed tumour lymphatic vessels …

Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …

Optical imaging in disease diagnosis and treatment benefits from high spatiotemporal
resolution and the availability of numerous optical agents. However, many optical imaging …

The delivery of medical agents to a specific diseased tissue or cell is critical for diagnosing
and treating patients. Nanomaterials are promising vehicles to transport agents that include …

Over the past two decades, there has been a growing interest in the use of plasmonic
nanoparticles as sources of heat remotely controlled by light, giving rise to the field of …

Nanoparticle delivery to solid tumours over the past ten years has stagnated at a median of
0.7% of the injected dose. Varying nanoparticle designs and strategies have yielded only …

Optical nanoparticles are promising diagnostic tools; however, their shallow optical imaging
depth and slow clearance from the body have impeded their use for in vivo disease …

The discovery of the medicinal properties of gold complexes has fuelled the design and
synthesis of new anticancer metallodrugs, which have received special attention due to their …