Liposomes are well recognised as effective drug delivery systems, with a range of products
approved, including follow on generic products. Current manufacturing processes used to …

Doxil®, the first FDA-approved nano-drug (1995), is based on three unrelated principles:(i)
prolonged drug circulation time and avoidance of the RES due to the use of PEGylated nano …

Introduction: Nanomedicine has emerged as a major field of academic research with direct
impact on human health. While a first generation of products has been successfully …

Although hydrophilic small molecule drugs are widely used in the clinic, their rapid
clearance, suboptimal biodistribution, low intracellular absorption and toxicity can limit their …

Nanomedicine is the application of nanotechnology to the discipline of medicine: the use of
nanoscale materials for the diagnosis, monitoring, control, prevention, and treatment of …

Combination therapy and nanotechnology offer a promising therapeutic method in cancer
treatment. By improving drug's pharmacokinetics, nanoparticulate systems increase the …

The necessity to develop more efficient, biocompatible, patient compliance, and safer
treatments in biomedical settings is receiving special attention using nanotechnology as a …

Extracellular vesicles (EVs) are membrane-derived particles surrounded by a (phospho)
lipid bilayer that are released by cells in the human body. In addition to direct cell-to-cell …

Employing combination therapy has become obligatory in cancer cases exhibiting high
tumor load, chemoresistant tumor population, and advanced disease stages. Realization of …

To achieve superior therapeutic efficacy, the combination chemotherapy using two or more
anticancer drugs in clinical practice has been generally accepted as a feasible strategy. On …