Endoplasmic reticulum (ER)-mitochondria contact sites are crucial to allow Ca 2+ flux
between them and a plethora of proteins participate in tethering both organelles together …

The endoplasmic reticulum (ER) is a cellular organelle that is physiologically responsible for
protein folding, calcium homeostasis, and lipid biosynthesis. Pathological stimuli such as …

Membrane contact sites (MCSs) are hubs allowing various cell organelles to coordinate their
activities. The dynamic nature of these sites and their small size hinder analysis by current …

Phosphatidylglycerol (PG) is a mitochondrial phospholipid required for mitochondrial cristae
structure and cardiolipin synthesis. PG must be remodeled to its mature form at the …

Mitochondria interact with the ER at structurally and functionally specialized membrane
contact sites known as mitochondria–ER contact sites (MERCs). Combining proximity …

Cellular homeostasis is crucial for the healthy functioning of the organism. Disruption of
cellular homeostasis activates endoplasmic reticulum (ER) stress coping responses …

An extensive network of chaperones and folding factors is responsible for maintaining a
functional proteome, which is the basis for cellular life. The underlying proteostatic …

Outer mitochondrial membrane (OMM) proteins communicate with the cytosol and other
organelles, including the endoplasmic reticulum. This communication is important in …

Ethnopharmacological relevance Excessive fat accumulation, biological clock dysregulation,
viral infections, and sustained inflammatory responses can lead to liver inflammation …

MicroRNAs (miRNAs) are important post-transcriptional factors involved in the regulation of
gene expression and play crucial roles in biological processes related to milk fat …