Antiseizure drugs (ASDs) prevent the occurrence of seizures; there is no evidence that they
have disease-modifying properties. In the more than 160 years that orally administered …

It is time to shift the arachidonic acid (ARA) paradigm from a harm-generating molecule to its
status of polyunsaturated fatty acid essential for normal health. ARA is an integral constituent …

There is growing evidence that ketone bodies, which are derived from fatty acid oxidation
and usually produced in fasting state or on high-fat diets have broad neuroprotective effects …

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the
structure, function, and motion of proteins for students, faculty, and researchers at all levels …

Inflammatory bowel diseases broadly categorized into Crohn's disease (CD) and ulcerative
colitis (UC), are chronic inflammatory disorders of the gastrointestinal tract with increasing …

Membrane ion channels are the fundamental electrical components in the nervous system.
Recent developments in X-ray crystallography and cryo-EM microscopy have revealed what …

Transient receptor potential (TRP) ion channels are evolutionarily ancient sensory proteins
that detect and integrate a wide range of physical and chemical stimuli. TRP channels are …

Potassium channels importantly contribute to the regulation of vascular smooth muscle
(VSM) contraction and growth. They are the dominant ion conductance of the VSM cell …

Kv1. 1 belongs to the Shaker subfamily of voltage-gated potassium channels and acts as a
critical regulator of neuronal excitability in the central and peripheral nervous systems …

Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in PKD 1 or
PKD 2 gene, encoding the polycystic kidney disease protein polycystin‐1 and the transient …