Synthesis strategies and medicinal value of pyrrole and its fused heterocyclic compounds

SS Fatahala, MS Mohamed, JY Sabry… - Medicinal …, 2022 - benthamdirect.com
In the last several decades, interest in pyrrole and pyrrolopyrimidine derivatives has
increased owing to their biological importance, such as anti-tumor, anti-microbial, anti …

Synthesis, dielectric properties, molecular docking and ADME studies of pyrrole-3-ones

İ Çapan, M Gümüş, H Gökce, H Çetin… - Journal of …, 2022 - Taylor & Francis
A novel series of pyrrole-3-one derivatives were synthesized using furan-3-one derivatives
and various aromatic amines. The synthesized compounds were identified by spectral …

2‐Amino‐5‐(cyanomethylsulfanyl)‐1H‐pyrroles from Propargylamines, Isothiocyanates, and Bromoacetonitrile by One‐Pot Synthetic Protocol

OA Tarasova, NA Nedolya, AI Albanov… - …, 2020 - Wiley Online Library
Tertiary propargylamines (such as N, N‐dialkylpropargylamines, N‐propargylpyrrolidine,‐
piperidine, and‐morpholine), isothiocyanates, and bromoacetonitrile have been shown to be …

An Efficient One-Pot Synthesis of 5-Sulfanyl-1-[2-(vinyloxy) ethyl]-1H-pyrrol-2-amines as Precursors of 1-Vinylpyrroles

OA Tarasova, NA Nedolya, AI Albanov… - Synthesis, 2022 - thieme-connect.com
Sequential processing of monolithiated tertiary propargylamines with 2-(vinyloxy) ethyl
isothiocyanate and t-BuOK–DMSO results in the introduction of a highly reactive 2-(vinyloxy) …