Health benefits of polyphenols and carotenoids in age‐related eye diseases

S Bungau, MM Abdel-Daim, DM Tit… - Oxidative medicine …, 2019 - Wiley Online Library
Oxidative stress and inflammation play a critical role in the initiation and progression of age‐
related ocular abnormalities as cataract, glaucoma, diabetic retinopathy, and macular …

Cellular responses following retinal injuries and therapeutic approaches for neurodegenerative diseases

N Cuenca, L Fernández-Sánchez, L Campello… - Progress in retinal and …, 2014 - Elsevier
Retinal neurodegenerative diseases like age-related macular degeneration, glaucoma,
diabetic retinopathy and retinitis pigmentosa each have a different etiology and …

Recent advances of natural polyphenols activators for Keap1‐Nrf2 signaling pathway

Y Zhou, Z Jiang, H Lu, Z Xu, R Tong… - Chemistry & …, 2019 - Wiley Online Library
Abstract The Keap1‐Nrf2/ARE signaling pathway is an important defense system against
exogenous and endogenous oxidative stress injury. The dysregulation of the signaling …

Protective effect of epigallocatechin-3-gallate (EGCG) in diseases with uncontrolled immune activation: could such a scenario be helpful to counteract COVID-19?

M Menegazzi, R Campagnari, M Bertoldi… - International Journal of …, 2020 - mdpi.com
Some coronavirus disease 2019 (COVID-19) patients develop acute pneumonia which can
result in a cytokine storm syndrome in response to Severe Acute Respiratory Syndrome …

Epigenetic changes induced by curcumin and other natural compounds

S Reuter, SC Gupta, B Park, A Goel, BB Aggarwal - Genes & nutrition, 2011 - Springer
Epigenetic regulation, which includes changes in DNA methylation, histone modifications,
and alteration in microRNA (miRNA) expression without any change in the DNA sequence …

Therapeutic activity of green tea epigallocatechin-3-gallate on metabolic diseases and non-alcoholic fatty liver diseases: The current updates

A James, K Wang, Y Wang - Nutrients, 2023 - mdpi.com
Green tea polyphenols have numerous functions including antioxidation and modulation of
various cellular proteins and are thus beneficial against metabolic diseases including …

From oxidative stress to inflammation in the posterior ocular diseases: diagnosis and treatment

A Dammak, F Huete-Toral, C Carpena-Torres… - Pharmaceutics, 2021 - mdpi.com
Most irreversible blindness observed with glaucoma and retina-related ocular diseases,
including age-related macular degeneration and diabetic retinopathy, have their origin in the …

Natural products: evidence for neuroprotection to be exploited in glaucoma

A Adornetto, L Rombolà, LA Morrone, C Nucci… - Nutrients, 2020 - mdpi.com
Glaucoma, a leading cause of irreversible blindness worldwide, is an optic neuropathy
characterized by the progressive death of retinal ganglion cells (RGCs). Elevated intraocular …

Glaucoma and antioxidants: Review and update

JJ Garcia-Medina, E Rubio-Velazquez… - Antioxidants, 2020 - mdpi.com
Glaucoma is a neurodegenerative disease characterised by the progressive degeneration of
retinal ganglion cells. Oxidative stress has been related to the cell death in this disease …

Oxidative stress and the role of NADPH oxidase in glaucoma

JC Fan Gaskin, MH Shah, EC Chan - Antioxidants, 2021 - mdpi.com
Glaucoma is characterised by loss of retinal ganglion cells, and their axons and many
pathophysiological processes are postulated to be involved. It is increasingly understood …