Evolution of the SARS‐CoV‐2 omicron variants BA. 1 to BA. 5: implications for immune escape and transmission
LB Shrestha, C Foster, W Rawlinson… - Reviews in Medical …, 2022 - Wiley Online Library
The first dominant SARS‐CoV‐2 Omicron variant BA. 1 harbours 35 mutations in its Spike
protein from the original SARS‐CoV‐2 variant that emerged late 2019. Soon after its …
protein from the original SARS‐CoV‐2 variant that emerged late 2019. Soon after its …
Persistent SARS-CoV-2 infection: significance and implications
HM Machkovech, AM Hahn, JG Wang… - The Lancet Infectious …, 2024 - thelancet.com
SARS-CoV-2 causes persistent infections in a subset of individuals, which is a major clinical
and public health problem that should be prioritised for further investigation for several …
and public health problem that should be prioritised for further investigation for several …
The molecular epidemiology of multiple zoonotic origins of SARS-CoV-2
Understanding the circumstances that lead to pandemics is important for their prevention.
We analyzed the genomic diversity of severe acute respiratory syndrome coronavirus 2 …
We analyzed the genomic diversity of severe acute respiratory syndrome coronavirus 2 …
Viral infection and transmission in a large, well-traced outbreak caused by the SARS-CoV-2 Delta variant
B Li, A Deng, K Li, Y Hu, Z Li, Y Shi, Q Xiong… - Nature …, 2022 - nature.com
Abstract The SARS-CoV-2 Delta variant has spread rapidly worldwide. To provide data on
its virological profile, we here report the first local transmission of Delta in mainland China …
its virological profile, we here report the first local transmission of Delta in mainland China …
Daily longitudinal sampling of SARS-CoV-2 infection reveals substantial heterogeneity in infectiousness
The dynamics of SARS-CoV-2 replication and shedding in humans remain poorly
understood. We captured the dynamics of infectious virus and viral RNA shedding during …
understood. We captured the dynamics of infectious virus and viral RNA shedding during …
SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency
Y Li, MC Choudhary, J Regan, J Boucau… - Science translational …, 2024 - science.org
Despite vaccination and antiviral therapies, immunocompromised individuals are at risk for
prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but the …
prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but the …
Prevalence of persistent SARS-CoV-2 in a large community surveillance study
Persistent SARS-CoV-2 infections may act as viral reservoirs that could seed future
outbreaks,,,–, give rise to highly divergent lineages,–and contribute to cases with post-acute …
outbreaks,,,–, give rise to highly divergent lineages,–and contribute to cases with post-acute …
Selection analysis identifies clusters of unusual mutational changes in Omicron lineage BA. 1 that likely impact Spike function
Among the 30 nonsynonymous nucleotide substitutions in the Omicron S-gene are 13 that
have only rarely been seen in other SARS-CoV-2 sequences. These mutations cluster within …
have only rarely been seen in other SARS-CoV-2 sequences. These mutations cluster within …
Accelerated SARS-CoV-2 intrahost evolution leading to distinct genotypes during chronic infection
The chronic infection hypothesis for novel severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variant emergence is increasingly gaining credence following the …
(SARS-CoV-2) variant emergence is increasingly gaining credence following the …
Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA. 1 variant through NSP6
Abstract Although the SARS-CoV-2 Omicron variant (BA. 1) spread rapidly across the world
and effectively evaded immune responses, its viral fitness in cell and animal models was …
and effectively evaded immune responses, its viral fitness in cell and animal models was …