Though the history of mankind, we are strongly fighting with infected diseases that are
induced by bacteria, fungi, viruses, and other pathogens. Although a variety of medicines …

The increasing awareness of the significance of microbial biofilms across different sectors is
continuously revealing new areas of opportunity in the development of innovative …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through March 1, 2020. Searches …

Aim This executive summary of the valvular heart disease guideline provides
recommendations for clinicians to diagnose and manage valvular heart disease as well as …

Pacemaker treatment for bradyarrhythmia was first approved for national health insurance
coverage in Japan in 1974, and its use rapidly became widespread thereafter …

Pacemakers, implantable cardiac defibrillators, and cardiac resynchronization therapy
devices are potentially life-saving treatments for a number of cardiac conditions, but are not …

From the 1Mayo Clinic, Jacksonville, Florida, 2Yale University School of Medicine, New
Haven, Connecticut, 3Cleveland Clinic Lerner College of Medicine of Case Western …

Background—Infective endocarditis is a potentially lethal disease that has undergone major
changes in both host and pathogen. The epidemiology of infective endocarditis has become …

LRRC4 is a novel relatively specific gene, which displays significant down-regulation in
primary brain tumor biopsies and has the potential to suppress brain tumor growth. In this …

Background Infections after placement of cardiac implantable electronic devices (CIEDs) are
associated with substantial morbidity and mortality. There is limited evidence on prophylactic …