The production of plastic products, which requires phthalate plasticizers, has resulted in the
problems for human health, especially that of reproductive health. Phthalate exposure can …

There is a need to better understand contemporary issues of nomenclature and group
construction around people with intersex variations shaping health research and practices …

We present a systematic evaluation of state-of-the-art algorithms for inferring gene
regulatory networks from single-cell transcriptional data. As the ground truth for assessing …

The gene regulatory structure of cells involves not only the regulatory relationship between
two genes, but also the cooperative associations of multiple genes. However, most gene …

Regulatory networks as large and complex as those implicated in cell-fate choice are
expected to exhibit intricate, very high-dimensional dynamics. Cell-fate choice, however, is a …

Gene regulatory network plays a crucial role in controlling the biological processes of living
creatures. Deciphering the complex gene regulatory networks from experimental data …

Cellular differentiation is one of the hallmarks of complex multicellularity, allowing individual
organisms to capitalize on among-cell functional diversity. The evolution of multicellularity is …

Complex living systems are thought to exist at the “edge of chaos” separating the ordered
dynamics of robust function from the disordered dynamics of rapid environmental …

Characterization of the differences between biological and random networks can reveal the
design principles that enable the robust realization of crucial biological functions including …

The dynamics of cellular mechanisms can be investigated through the analysis of networks.
One of the simplest but most popular modeling strategies involves logic-based models …