The outcome of hematopoietic stem cell transplantation (HSCT) is controlled by genetic
factors among which the leukocyte antigen human leukocyte antigen (HLA) matching is most …

Multiple candidate gene-association studies of non-HLA single-nucleotide polymorphisms
(SNPs) and outcomes after blood or marrow transplant (BMT) have been conducted. We …

HLA matching, transplantation technique, or underlying disease greatly influences the
probability of long-term transplantation success. It has been hypothesised that genetic …

T cell activation plays a crucial role in the development of acute graft versus host disease
(aGvHD). Cytotoxic T cell antigen-4 (CTLA-4) is a co-inhibitory molecule that negatively …

Background Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been
established as an effective treatment for patients with hematological malignancies. Disease …

We retrospectively investigated the impact of CTLA-4 polymorphism on outcomes for adult
patients who received single-unit cord blood transplantation (CBT) at our institution. CTLA-4 …

Objective Relapse following allogeneic hematopoietic stem cell transplantation (HSCT) is
still linked to a poor prognosis. Mainly, donors T‐cells mediate the graft‐versus‐leukemia …

Purpose Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative approach
for a variety of hematological diseases; however, it is still associated with substantial …

Objective Cytotoxic T-lymphocyte antigen 4 (CTLA-4) polymorphisms at positions of+ 49 and
CT60 in donors have been reported to influence clinical outcome following allogeneic …

Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) plays an important role in the
initiation and development of Graves' disease (GD), especially CTLA-4+ 49A/G …