Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen
species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants …

Ascorbic acid, as a one of the basic exogenous vitamins, occurs in the body in the form of
ascorbate, known for its strong antioxidant and anti-inflammatory properties. The presented …

The activation of ferroptosis is a new effective way to treat drug-resistant solid tumors.
Ferroptosis is an iron-mediated form of cell death caused by the accumulation of lipid …

Oxidative stress is a pathological condition occurring due to an imbalance between the
oxidants and antioxidant defense systems in the body. Nuclear factor E2-related factor 2 …

Elevated intracellular reactive oxygen species (ROS) and antioxidant defense systems have
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …

Ferroptosis is a recently discovered distinct type of regulated cell death caused by the
accumulation of lipid-based ROS. Metabolism and expression of specific genes affect the …

Breast cancer has become a serious threat to women's health. Cancer progression is mainly
derived from resistance to apoptosis induced by procedures or therapies. Therefore, new …

Neurodegenerative diseases (NDs) cause progressive loss of neurons in nervous system.
NDs are categorized as acute NDs such as stroke and head injury, besides chronic NDs …

Glutathione (GSH), often referred to as “the master antioxidant,” participates not only in
antioxidant defense systems, but many metabolic processes, and therefore its role cannot be …

Breast cancer is the second leading cancer among all types of cancers. It accounts for 12%
of the total cases of cancers. The complex and heterogeneous nature of breast cancer …