The peptidyl transferase center: a window to the past

MR Tirumalai, M Rivas, Q Tran… - … and Molecular Biology …, 2021 - Am Soc Microbiol
SUMMARY In his 2001 article,“Translation: in retrospect and prospect,” the late Carl Woese
made a prescient observation that there was a need for the then-current view of translation …

Phylogenies of the 16S rRNA gene and its hypervariable regions lack concordance with core genome phylogenies

HB Hassler, B Probert, C Moore, E Lawson… - Microbiome, 2022 - Springer
Abstract Background The 16S rRNA gene is used extensively in bacterial phylogenetics, in
species delineation, and now widely in microbiome studies. However, the gene suffers from …

Widespread use of unconventional targeting signals in mitochondrial ribosome proteins

YS Bykov, T Flohr, F Boos, N Zung, JM Herrmann… - The EMBO …, 2022 - embopress.org
Mitochondrial ribosomes are complex molecular machines indispensable for respiration.
Their assembly involves the import of several dozens of mitochondrial ribosomal proteins …

All these screens that we've done: how functional genetic screens have informed our understanding of ribosome biogenesis

CM Harold - Bioscience Reports, 2023 - portlandpress.com
Ribosome biogenesis is the complex and essential process that ultimately leads to the
synthesis of cellular proteins. Understanding each step of this essential process is …

Amphioxus ribosomal proteins RPS15, RPS18, RPS19 and RPS30-precursor act as immune effectors via killing or agglutinating bacteria

C Chen, J Yuan, G Ji, S Zhang, Z Gao - Fish & Shellfish Immunology, 2021 - Elsevier
Previous studies show that some ribosomal proteins perform immune effector functions via
killing bacteria directly. However, it remains largely unknown about other effector functions …

Conservation and coevolution determine evolvability of different classes of disordered residues in human intrinsically disordered proteins

S Basu, RP Bahadur - Proteins: Structure, Function, and …, 2022 - Wiley Online Library
Abstract Structure, function, and evolution are interdependent properties of proteins.
Diversity of protein functions arising from structural variations is a potential driving force …

Sequence and evolutionary analysis of bacterial ribosomal S1 proteins

E Deryusheva, A Machulin, M Matyunin… - Proteins: Structure …, 2021 - Wiley Online Library
The multi‐domain bacterial S1 protein is the largest and most functionally important
ribosomal protein of the 30S subunit, which interacts with both mRNA and proteins. The …

Mitochondrial ribosomal proteins developed unconventional mitochondrial targeting signals due to structural constraints

YS Bykov, T Flohr, F Boos, JM Herrmann, M Schuldiner - bioRxiv, 2021 - biorxiv.org
Mitochondrial ribosomes are complex molecular machines indispensable for respiration.
Their assembly involves the import of several dozens of mitochondrial ribosomal proteins …